Improved nuclear localization of DNA-binding polyamides
نویسندگان
چکیده
منابع مشابه
Improved nuclear localization of DNA-binding polyamides
Regulation of endogenous genes by DNA-binding polyamides requires effective nuclear localization. Previous work employing confocal microscopy to study uptake of fluorophore-labeled polyamides has demonstrated the difficulty of predicting a priori the nuclear uptake of a given polyamide. The data suggest that dye identity influences uptake sufficiently such that a dye-conjugate cannot be used as...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2006
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkl1042